1/4 backs with 1/2 IPB nailer dado in to top bottom and sides 9/16 back .
I did as cabinet maker for a while but found that doweling the nailers was an extra step I didn't want to do so I went to industrial hot glue when in the case clamp all around the perimeter , then press in the 1/2 " nailers to the glue and run a pattern on them before pressing to back as well. Nailers are cut 1/16 less than top and bottom length so they fit in easy when in the clamp. Then we run around the joint of the case to the nailer with a senclamp gun and give it a physical fastener as well, pulls it all tight.
Tested and it makes a strong box so I am confident it will hold up on 42" uppers etc .
I like having the 9/16 to work with in case we have lumpy walks to install on , the solid backs flush with the ends can create a lot of shimming to install when you get bad walls and don't allow you to just take a planer to the sides , top , bottom etc if you need a little room for wall condition etc..
I keep the nailers out of the nest and just cut them up on the slider while the first couple of nests are being cut , then start banding parts and by the time nests are cut I'm all caught up with the banding and ready to horizontal bore with all parts on cart ready for assembly.
Have an area by the case clamp where all the nailers stack so it keeps less parts in the carts and assby tables.
Best I've come up with so far but always looking for a better way .